60 Selected Studies By Hanon Pdf 24
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In terms of lifestyle advice, one study found that only 31% of people were receiving advice on the importance of stopping smoking, avoiding alcohol and controlling blood pressure [24]. Another study found that the majority of people with dementia were receiving advice on physical activity [25].
The most commonly used antihypertensive drugs were ACE inhibitors (2-32%), angiotensin receptor blockers (0-28%), calcium channel blockers (0-23%), beta-blockers (0-10%) and thiazides (4-17%) [24, 26]. The choice of antihypertensive was not statistically associated with dementia.
The level of blood pressure control was evaluated across these studies. Only two studies reported a formal evaluation of the level of blood pressure control. One of these studies found that the level of blood pressure control was lower than expected, with 61% of people with dementia on no antihypertensive drugs, only 21% prescribed ACE inhibitors and 3% prescribed angiotensin receptor blockers [15]. The other study found that only 25% of people with dementia were receiving adequate blood pressure control [19].
The studies in this review mainly focused on patients with mild to moderate dementia. However, an additional review of the literature could be useful. This would involve a systematic review, carried out according to the standard requirements of an SR, but this review would be limited to articles that have been published since the last systematic review was completed (2004) and with the aim of determining whether the available evidence supports the use of antihypertensive drugs in people with dementia. The study would examine the strength of the evidence base for each of the available antihypertensives in people with dementia. The study would also examine the strength of the evidence base for the potential therapeutic benefit of antihypertensive drugs in people with dementia. In this latter review the search terms used should include “randomized controlled trial” and “clinical trial”, as we would be searching for studies that have been carried out and published in the last 10 years. If there is sufficient data for the drugs of interest, it would be worth considering the review of the literature in a meta-analysis to see whether any conclusions can be drawn about the effectiveness of antihypertensive drugs in people with dementia, and the strength of the evidence base for each of the potential therapeutic benefit of antihypertensive drugs in people with dementia.
In early 2014 the Cochrane Dementia and Cognitive Improvement Group undertook a systematic review of randomised controlled trials of antihypertensives in people with dementia [20]. Full details are available on the group’s website [37]. The findings from this review concluded that antihypertensives are beneficial for the treatment of hypertension in people with dementia and that systolic blood pressure (SBP) should be lowered to 827ec27edc